Yes, I would check both boxes.
For example, the "Better new post interface for mobile users" removes some of the text from the Edit box buttons. It is definitely an improvement when working on small screens.
The "Responsive layout (BETA)" option is still in development, (See the
Mobile Optimization topic), but I am definitely seeing improvement on my phone and tablet on the site I am testing the feature on.
Volunteer Helper - but recommending that users move off the platform!
Once the admin for GregHelp now deleted.